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How 10mL of fluid and a blanket can save your life (and a few interesting facts about clotting mechanisms)

First of all, the 10mL of fluid is not saline. In fact, two decades of research tells us that aggressive crystalloid resuscitation is harmful.[1]

Saline presents many challenges when used to resuscitate hypotensive patients:

  • It’s acidic nature causes the body to use and deplete its natural buffers which leads to increased acidosis
  • It is pro-inflammatory and is associated with poor outcomes
  • It dilutes clotting factors
  • It is often cold and contributes to hypothermia

All of this increases mortality by exposing the patient all three aspects of the Trauma Triad of Death:

  • Hypothermia
  • Coagulopathy
  • Metabolic Acidosis

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